분자세포생물학연구실 (13동 208호)
· 진핵생물의 DNA 복제 및 복제기 조절
· DNA 수선 및 세포주기의 checkpoint 조절
· 중등 생물교과 교육자료 개발연구
2002. 12. – 현재.
서울대학교 사범대학 생물교육과 교수
1994. 7. – 2002. 2.
Memorial Sloan-Kettering Cancer Center, 연구원
· Shin G, Jeong D, Kim H, Im JS, Lee JK. RecQL4 tethering on the pre-replicative complex induces unscheduled origin activation and replication stress in human cells. J Biol Chem 2019 Nov 1, 294(44): 16255-16265
· Park SY, Kim H, Im JS, Lee JK. ATM activation is impaired in human cells defective in RecQL4 helicase activity. Biochem Biophysic Res Commun. 2019 Feb. 5, 509(2):379-383
· Im JS, Park SY, Cho WH, Bae SH, Hurwitz J, Lee JK. RecQL4 is required for the association of Mcm10 and Ctf4 with replication origins in human cells. Cell Cycle. 2015 Apr 3;14(7):1001-9.
· Cho WH, Kang YH, An YY, Tappin I, Hurwitz J, Lee JK, Human Tim-Tipin complex affects the biochemical properties of the replicative DNA helicase and DNA polymerases, Proc Natl Acad Sci USA. 2013, Feb. 12, 110(7): 2523-2527
· Im JS, Ki SH, Farina A, Jung DS, Hurwitz J, Lee JK. Assembly of the Cdc45-Mcm2-7-GINS complex in human cells requires the Ctf4/And1, RecQL4, and Mcm10 proteins. Proc Natl Acad Sci USA. 2009, Sep 15, 106(37): 15628-15632.
