분자유전학연구실 (13동 213호)
- DNA 복제 손상 및 복구 기전 연구
- 복제포크 안정성과 재시작 조절
2025. 09. – 현재.
서울대학교 사범대학 생물교육과 조교수
2023-2025
1. Kim, Y.; Ha, N. Y.; Kang, M.-S.; Ryu, E.; Yi, G.; Yoo, J.; Kang, N.; Kim, B.-G.; Myung, K.; Kang, S. ATAD5-BAZ1B interaction modulates PCNA ubiquitination during DNA repair. Nature Communications 2024, 15(1), 1–17.
2. Morimoto, M.¹; Ryu, E.¹; Steger, J. B.; Dixit, A.; Saito, Y.; Yoo, J.; …; Malicdan, C. V. M. Expanding the genetic and phenotypic landscape of replication factor C complex-related disorders: RFC4 deficiency is linked to a multisystemic disorder. The American Journal of Human Genetics 2024, 111(9), 1970–1993.
3. Ryu, E.; Yoo, J.; Kang, M.-S.; Ha, N. Y.; Jang, Y.; Kim, J.; …; Kang, S. ATAD5 functions as a regulatory platform for Ub–PCNA deubiquitination. PNAS 2024, 121(34), e2315759121.
4. Park, S. H.; Kim, N.; Kang, N.; Ryu, E.; Lee, E. A.; Ra, J. S.; …; Lee, K. Y. Short-range end resection requires ATAD5-mediated PCNA unloading for faithful homologous recombination. Nucleic Acids Research 2023, 51(19), 10519–10535.
5. Ryu, E.; Ha, N. Y.; Jung, W.; Yoo, J.; Myung, K.; Kang, S. Distinct motifs in ATAD5 C-terminal domain modulate PCNA unloading process. Cells 2022, 11(11), 1832.
6. Espanola, S. G.; Song, H.; Ryu, E.; Saxena, A.; Kim, E.-S.; …; Lee, Y. Haematopoietic stem cell-dependent Notch transcription is mediated by p53 through the Histone chaperone Supt16h. Nature Cell Biology 2020, 22(12), 1411.
7. Kang, M.-S.; Kim, J.; Ryu, E.; Ha, N. Y.; Hwang, S.; …; Kang, S. PCNA Unloading Is Negatively Regulated by BET Proteins. Cell Reports 2019, 29(13), 4632.
8. Kang, M.-S.¹; Ryu, E.¹; Lee, S. W.¹; Park, J.; Ha, N. Y.; …; Myung, K. Regulation of PCNA cycling on replicating DNA by RFC and RFC-like complexes. Nature Communications 2019, 10(1), 2420.
